dsh-bio-galatea
Protein structure prediction and sequence design toolkit providing 19 tools for ProteinMPNN, ESMFold, interface analysis, and campaign scheduling.
Install
$ dsh plugin --profile web add @dsh-bio/dsh-bio-galateaPlugin Overview & Capabilities
AI-assisted organization based on the public repository snapshot. The content must be grounded in source evidence and does not replace compatibility or security verification.
Key Capabilities
- Execute inverse folding and sequence design via ProteinMPNN, SolubleMPNN, and LigandMPNN
- Predict single-chain protein structures and perform refolding verification with ESMFold
- Analyze complex binding interfaces including contacts, hydrogen bonds, salt bridges, and buried SASA
- Perform sequence physicochemical scoring (pI, charge, GRAVY, hydrophobic moment, aggregation proxies)
- Cluster candidates and manage multi-round redesign iteration ledgers, quotas, and consensus ranking
- Audit campaign coverage, calculate contact consensus, and schedule multi-target design budgets
Useful For
- Designing binder, enzyme, and nanobody sequences from 3D protein structures directly within DeepSeek Harness
- Validating single-chain folding fidelity and monomer stability following computational design
- Filtering, clustering, and selecting candidate portfolios for experimental validation
Who It Fits
- Computational biologists
- Protein engineers
- Bioinformatics researchers using DeepSeek Harness
Documented Limitations
- Does not run complex co-folding or massive backbone generation locally due to consumer hardware constraints
- ESMFold model weights require significant local disk storage (approx. 2.5GB)
- F2Å metric and default refold thresholds require experimental calibration
DSH Compatibility
Version-specific runtime evidence collected by DSH Plugin. A missing result means we have not tested that combination yet.
Security Signals
Objective signals discovered from package metadata and source inspection. These are not a guarantee that a plugin is safe.
package.json declares 0 runtime, 0 development, 1 peer, and 0 optional dependencies.
package.json declares DSH bundle metadata.
GitHub reports the repository license as MIT.
A root package.json was captured and can be inspected by the registry.
Public GitHub source metadata is available for this registry snapshot.
Source & Registry Notes
Public provenance, Registry classification, and the latest source check for this entry, kept separate from runtime verification.
- Source repository
- moonbowterfly/dsh-bio-galatea
- Registry source
- GitHub · dsh-plugin topic
- Registry classification
- Plugin
- Source checked
- f0503f1 · 2026-10-25
This project is independently indexed from public source information. DSH Plugin is not affiliated with DeepSeek or the plugin author. Always check the author repository before installation.
Repository Activity
- GitHub stars
- 0GitHub stars
- Forks
- 0
- Open issues
- 0
- Last commit
- 2026-10-23
- Last release
- 2026-10-23
Related DSH Plugins
Ranked by overlapping capabilities, use cases, plugin type, categories, and DSH profile.
Free and multi-engine web search provider for DeepSeek Harness with automatic fallback and web settings UI.
View plugin →High-performance native file, shell, and PTC operations toolkit for DeepSeek Harness.
View plugin →Security red-teaming and prompt rule management plugin for DeepSeek Harness web and desktop profiles.
View plugin →Connect DeepSeek Harness to your real, logged-in Chrome or Edge browser for automated navigation, inspections, and web debugging.
View plugin →