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dsh-bio-human-microbiome-function-mining

DeepSeek Harness plugin bundle for human microbiome enzyme discovery and functional dark matter mining.

Terminal & TUIDeveloper ToolsSecurity & PolicySkills & WorkflowsRemote Execution
0GitHub Stars0ForksUpdated2026-10-12

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Plugin Overview & Capabilities

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dsh-bio-human-microbiome-function-mining is a DeepSeek Harness plugin bundle designed to discover candidate enzymes from human-associated microbial genomes. It structures target identification, CD-HIT deduplication, DIAMOND sequence screening, US-align structure alignment, DEER fallbacks, FedKEA functional validation, and literature auditing into an auditable evidence chain with experimental design outputs.

Key Capabilities

  • Converts target enzymes, EC numbers, or substrate-product pairs into standardized target function cards
  • Orchestrates CD-HIT deduplication and DIAMOND sequence homology searches against candidate proteomes
  • Manages structural prediction and US-align comparisons with fallback to DEER retrieval
  • Integrates FedKEA enzyme classification and verified literature citations with PMID/DOI tracking
  • Computes deterministic candidate ranking and compiles reproducible wet-lab experimental designs

Useful For

  • Discovering novel metabolic enzymes in human microbiome datasets
  • Predicting functional dark matter and uncharacterized microbial proteins matching specific reactions
  • Drafting falsifiable hypotheses and wet-lab validation protocols for candidate microbial enzymes

Who It Fits

  • Bioinformatics researchers
  • Microbiome scientists
  • Computational biologists developing automated protein discovery pipelines

Documented Limitations

  • Requires external bioinformatics binaries (DIAMOND, CD-HIT, US-align, DEER, Bakta, FedKEA) to be installed and configured locally by the user
  • Does not bundle compute infrastructure or biological sequence/structure databases

DSH Compatibility

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Security Signals

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Dependency Counts

package.json declares 0 runtime, 0 development, 3 peer, and 0 optional dependencies.

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Dsh Bundle Declared

package.json declares DSH bundle metadata.

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License Declared

GitHub reports the repository license as MIT.

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Package Manifest Available

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Postinstall Script Detected

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Source Available

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Source & Registry Notes

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Source repository
Liuyixin-lily/dsh-bio-human-microbiome-function-mining
Registry source
GitHub · dsh-plugin topic
Registry classification
Plugin Bundle
Source checked
43d0233 · 2026-10-25

This project is independently indexed from public source information. DSH Plugin is not affiliated with DeepSeek or the plugin author. Always check the author repository before installation.

Repository Activity

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Last commit
2026-10-12
Last release
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